Qufeng Xuanbi Formula inhibited benzo[a]pyrene-induced aggravated asthma airway mucus secretion by AhR/ROS/ERK pathway.

Bo-Han Wang,Ling-Ling Tang,Xian-Hong Sun,Qian Zhang,Chun-Yang Liu,Xiao-Na Zhang,Ke-Yao Yu,Ying Yang,Jun Hu,Xiao-Lu Shi,Yue Wang,Li Liu

Journal of ethnopharmacology（2023）

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摘要

QFXBF can ameliorate mucus secretion in BaP-induced aggravated asthmatic mice and 16HBE cells, and the specific mechanism may be related to the inhibition of the AhR/ROS/ERK signaling pathway.

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关键词

Asthma,Qufeng Xuanbi formula,benzo[a]pyrene,MUC5AC,AhR/ROS/ERK pathway

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