Advances in Phytochemistry and Modern Pharmacology of Saposhnikovia Divaricata (Turcz.) Schischk

Saposhnikovia divaricata (Turcz.) Schischk ( S. divaricata , Fangfeng) is a herb in the Apiaceae family, and its root has been used since the Western Han Dynasty (202 B.C.). Chromones and coumarins are the pharmacologically active substances in S. divaricata . Modern phytochemical and pharmacological studies have demonstrated their antipyretic, analgesic, anti-inflammatory, antioxidant, anti-tumor, and anticoagulant activities. Technological and analytical strategy theory advancements have yielded novel results; however, most investigations have been limited to the main active substances—chromones and coumarins. Hence, we reviewed studies related to the chemical composition and pharmacological activity of S. divaricata , analyzed the developing trends and challenges, and proposed that research should focus on components’ synergistic effects. We also suggested that, the structure-effect relationship should be prioritized in advanced research.