Modelling the pathology and treatment of cardiac fibrosis in vascularised atrial and ventricular cardiac microtissues.

Jasmeet S Reyat,Alessandro di Maio,Beata Grygielska,Jeremy Pike,Samuel Kemble,Antonio Rodriguez-Romero,Christina Simoglou Karali,Adam P Croft,Bethan Psaila,Filipa Simões,Julie Rayes,Abdullah O Khan

Frontiers in cardiovascular medicine（2023）

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摘要

In conclusion, we present a novel methodology for the generation of chamber-specific cardiac microtissues that is highly scalable and allows for the multi-parametric assessment of cardiac remodelling and pharmacological screening.

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cardiac fibrosis

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