Novel, non-colonizing, single-strain live biotherapeutic product ADS024 protects against Clostridioides difficile infection challenge in vivo .

Christopher K Murphy,Michelle M O'Donnell,James W Hegarty,Sarah Schulz,Colin Hill,R Paul Ross,Mary C Rea,Ronald Farquhar,Laurent Chesnel

World journal of gastrointestinal pathophysiology（2023）

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摘要

Our findings, demonstrating efficacy of ADS024 in protecting against CDI challenge in mouse models, support the use of ADS024 in preventing recurrent CDI following standard antibiotic treatment.

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关键词

live biotherapeutic product ads024,infection challenge,difficile</i> infection,non-colonizing,single-strain

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