Impact of body mass index on outcome and treatment-related toxicity in young adults with acute lymphoblastic leukemia.

Christina Egnell,Helene Hallböök,Mats Heyman,Ulla Wartiovaara-Kautto,Petter Quist-Paulsen,Kjeld Schmiegelow,Laimonas Griskevicius,Katrin Palk,Nina Toft,Ulrik Malthe Overgaard,Arja Harila,Susanna Ranta

Acta oncologica (Stockholm, Sweden)（2023）

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摘要

Severe obesity is associated with worse EFS in young adults treated according to the non-HR arms of the NOPHO ALL2008 protocol. Poorer outcome is explained with a higher risk of relapse, possibly due to under treatment, and not caused by excess therapy-related mortality.

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关键词

Obesity, acute lymphoblastic leukemia, toxicity, young adults, body mass index

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