Detailed characterisation of invasive aspergillosis in a murine model of X-linked chronic granulomatous disease shows new insights in infections caused by Aspergillus fumigatus versus Aspergillus nidulans .

Jill King,Ivy M Dambuza,Delyth M Reid,Raif Yuecel,Gordon D Brown,Adilia Warris

Frontiers in cellular and infection microbiology（2023）

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摘要

We have provided an in-depth characterisation of the immune response to pulmonary aspergillosis in an X-linked CGD murine model. This provides the first description of distinct pulmonary inflammatory environments in and infection in X-linked CGD and identifies several new avenues for further research.

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关键词

invasive aspergillosis,aspergillus fumigatus,chronic granulomatous disease,infections,x-linked

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