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Safety and efficacy of anti-BCMA CAR-T cell therapy in older adults with multiple myeloma: A systematic review and meta-analysis

Othman Salim Akhtar, Ba Aqeel Sheeba, Farhan Azad, Lauren Alessi,Doris Hansen,Melissa Alsina,Rachid Baz,Kenneth Shain, Ariel Grajales Cruz,Omar Castaneda Puglianini,Hien Liu,Brandon Blue,Taiga Nishihori,Mohammed Al Jumayli,Martine Extermann,Frederick L. Locke,Rahul Mhaskar,Ciara Louise Freeman

Journal of geriatric oncology（2023）

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摘要
Older adults experience comparable outcomes to younger patients with anti-BCMA CAR-T therapy, albeit with numerically higher rates of neurotoxicity.
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关键词
Multiple myeloma,Anti-BCMA CAR-T therapy,Older adults,Cellular therapy,CAR-T therapy
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