The negative effect of concomitant medications on immunotherapy in non-small cell lung cancer: An umbrella review.

Jixin Chen,Shuqi Chen,Huiyan Luo,Shunqin Long,Xiaobing Yang,Wenfeng He,Wanyin Wu,Sumei Wang

International immunopharmacology（2023）

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摘要

The concurrent usage of PPIs or steroids adversely affects the survival of patients with NSCLC receiving immunotherapy. Future investigations are required to ascertain whether these adverse effects are primarily attributed to the comorbidities or the concurrent medications.

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关键词

Immunotherapy, Concomitant medications, NSCLC, Umbrella review, PD-1/PD-L1 inhibitor

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