Editorial: Neuropathology of COVID-19

Liisa Myllykangas, University of Helsinki, Finland Currently, there are more than 375 000 articles in Pubmed covering COVID-19 and SARS-CoV-2, but very few of them have been focused on COVID-19-associated neuropathology.These neuropathological studies have been mostly based on relatively small cohort sizes that have described variable tissue changes, mainly focusing on severe adult cases. Although they have formed the basis for our understanding of COVID-19-associated neuropathology, many important knowledge gaps still exist. For example, it is still unclear if the neuropathological changes are caused by direct invasion of the virus into the brain, or rather represent indirect consequences of systemic disease. The immune-mediated mechanisms and in particular the All the authors are acknowledged for their significant contributions towards this Research topic. Hopefully this collection of papers will encourage further studies in this important field.