A pilot, masked, randomized controlled trial to evaluate local gentamicin versus saline in open tibial fractures (pGO-Tibia).

Billy T Haonga, Patrick Ngunyale,Ericka P von Kaeppler,Claire A Donnelley,Nae Y Won,Edmund N Eliezer,Kelsey Brown,Michael Flores,Jamieson M O'Marr,Patricia Rodarte,Mayur Urva,Abigail Cortez,Travis Porco,Saam Morshed,David W Shearer

OTA international : the open access journal of orthopaedic trauma（2023）

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摘要

This pilot study is among the first to evaluate locally administered gentamicin in open tibial fractures. Results indicate a rigorous clinical trial with acceptable rates of enrollment and follow-up to address this topic is possible in this setting.

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关键词

open tibial fractures,local gentamicin,saline,pgo-tibia

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