Liver disease progression in patients with alpha-1 antitrypsin deficiency and protease inhibitor ZZ genotype with or without lung disease.

Tiffany Wu,May Hagiwara,Esteban Gnass,Hannah Barman, David Sasson, William Treem,Kaili Ren,Ed G Marins,Chitra Karki,Harmeet Malhi

Alimentary pharmacology & therapeutics（2023）

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摘要

In patients with AATD and lung disease, there is a delay in the diagnosis of comorbid liver disease. Our findings suggest that liver disease may progress more rapidly in patients without comorbid lung disease.

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