Five-Day Spacing of Two Fractionated Ablative Radiotherapies Enhances Antitumor Immunity

Hyunkyung Kim,Eunju Lee, Haeun Cho,Eunji Kim,Won Il Jang,Kwangmo Yang,Yoon-Jin Lee,Tae-Jin Kim,Mi-Sook Kim

International Journal of Radiation Oncology*Biology*Physics（2024）

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摘要

Compared to the one-day interval RT, the five-day interval RT scheme demonstrated enhanced anti-tumor immunity of CD8 T-cells associated with inhibition of M-MDSCs. Enhancing anti-tumor immunity led to significant improvements in both primary tumor control and the abscopal effect.

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immunity,five-day,anti-tumor

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