Anakinra in cerebral haemorrhage to target secondary injury resulting from neuroinflammation (ACTION): Study protocol of a phase II randomised clinical trial.

M P Cliteur,A G van der Kolk,G Hannink,J Hofmeijer, Wmt Jolink, Cjm Klijn, Fhbm Schreuder

European stroke journal（2023）

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摘要

The ACTION trial will provide insight into whether targeting interleukin-1 beta in the early time window after ICH onset could ameliorate secondary brain injury. This may contribute to the development of new treatment options to improve clinical outcome after ICH.

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