Serious immune-related upper gastrointestinal toxicity of immune checkpoint inhibitors: a multicenter case series.

Clément Bresteau,Pauline Bonnet,Caroline Robert,Charlotte Mussini,Philippe Saiag, Bruno Buecher,Celeste Lebbe,Matthieu Allez,Robert Benamouzig,Hervé Hagège,Hakim Bécheur,Antoine Meyer,Franck Carbonnel

Journal of gastroenterology and hepatology（2023）

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摘要

ICI cause severe UGI IrAEs, which are associated with enterocolitis in approximately half of the patients. Most patients with UGI IrAEs respond to corticosteroids or infliximab. These data support the recommendation to treat these patients without delay and in the same way as those with enterocolitis.

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关键词

Duodenitis, Gastritis, Immune checkpoint blockade, Immune-related adverse event

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