Possible involvement of inflammasomes on the post-stroke cognitive impairment in a mouse model of embolic cerebral infarct

Physiology & behavior(2023)

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摘要
•Acetic acid-induced ECI mice showed long-term memory impairment.•The p-GluR1 levels at Ser831 and Ser845 decreased in the dorsal hippocampi of ECI mice.•IL-1β, IL-18, and TNF-α levels increased in the dorsal hippocampus of ECI mice.•Caspase-1 and ASC/TMS1 levels increased in the dorsal hippocampus of ECI mice.
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关键词
Post-stroke cognitive impairment,Embolic cerebral infarct,Microglia,AMPA receptor,Inflammasome
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