Establishment of baseline urinary antimicrobial peptide levels by age: a prospective observational study.

Jeffrey M Caterino,Julie A Stephens,Randell Wexler,Carlos A Camargo,Katherine M Hunold,Lai Wei,David Hains,Lauren T Southerland,Jason J Bischof,Andrew Schwaderer

The journals of gerontology. Series A, Biological sciences and medical sciences（2023）

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摘要

Baseline urinary HNP 1-3, HD5, and LL-37 did not vary with age. Older adults had lower baseline hBD-2. This finding has implications for the potential use of urinary AMPs as diagnostic markers and will facilitate further investigation into the role of innate immunity in UTI susceptibility in older adults.

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Biomarkers, Infection, Urological

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