A nucleotide diphosphate kinase mediates tethering between mitochondria prior to fusion.
The Journal of cell biology(2023)
摘要
Mitochondrial fusion plays an important role in both their structure and function. In this issue, Su et al. (2023. J. Cell Biol.https://doi.org/10.1083/jcb.202301091) report that a nucleoside diphosphate kinase, NME3, facilitates mitochondrial tethering prior to fusion through its direct membrane-binding and hexamerization but not its kinase activity.
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关键词
diphosphate kinase,mitochondria,nucleotide,fusion
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