A novel risk variant block across introns 36-45 of CACNA1C for schizophrenia: a cohort-wise replication and cerebral region-wide validation study.

Xiaoyun Guo,Shibin Wang,Xiandong Lin,Zuxing Wang,Yikai Dou,Yuping Cao,Yong Zhang,Xinqun Luo,Longli Kang,Ting Yu,Zhiren Wang,Yunlong Tan, Shenshen Gao,Hangxiao Zheng,Fen Zhao, Huifen Wang,Kesheng Wang, Fan Xie,Wenzhong Chen,Xinguang Luo

Psychiatric genetics（2023）

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摘要

We have identified a novel and functional risk variant block at CACNA1C for schizophrenia, providing further evidence for the important role of this gene in the pathogenesis of schizophrenia.

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关键词

cacna1c,schizophrenia,cohort-wise,region-wide

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