Lignin/Puerarin Nanoparticle-Incorporated Hydrogel Improves Angiogenesis through Puerarin-Induced Autophagy Activation.

Yingjing Pan,Tianci Lin,Longquan Shao,Yulin Zhang,Qiao Han,Liyuan Sheng,Rui Guo,Ting Sun,Yanli Zhang

International journal of nanomedicine（2023）

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摘要

The puerarin-attached lignin nanoparticle-incorporated hydrogel effectively alleviated blood perfusion in mice with hind-limb ischemia. Puerarin has a prominent proangiogenic effect. The potential mechanisms might be that puerarin-mediated autophagy activation and increase in PPARβ/δ.

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关键词

angiogenesis,hydrogel,autophagy,nanoparticle-incorporated,puerarin-induced

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