Human umbilical cord mesenchymal stem cell-derived exosomes attenuate neuroinflammation and oxidative stress through the NRF2/NF-κB/NLRP3 pathway.

Ji Che,Hui Wang,Jing Dong,Yuanyuan Wu,Haichao Zhang,Lei Fu,Jun Zhang

CNS neuroscience & therapeutics（2023）

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摘要

hUC-MSC-derived exosomes ameliorated LPS/H O -induced neuroinflammation and oxidative stress by inhibiting the microglial NRF2/NF-κB/NLRP3 signaling pathway.

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