TMEM132D and VIPR2 Polymorphisms as Genetic Risk Loci for Retinal Detachment: A Genome-Wide Association Study and Polygenic Risk Score Analysis.

Hao-Kai Chuang,Ai-Ru Hsieh, Tien-Yap Ang, Szu-Wen Chen,Yi-Ping Yang, Hung-Juei Huang,Shih-Hwa Chiou,Tai-Chi Lin,Shih-Jen Chen,Chih-Chien Hsu,De-Kuang Hwang

Investigative ophthalmology & visual science（2023）

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摘要

TMEM132D and VIPR2 polymorphisms are genetic candidates linked to RD in Han Chinese populations. Our proposed PRS was effective at discriminating high-risk from low-risk individuals.

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关键词

retinal detachment,vipr2 polymorphisms,genetic risk loci,tmem132d,genome-wide

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