Subclinical synovial proliferation in patients with severe haemophilia A: The value of ultrasound screening and biochemical markers.

Eline D P van Bergen,Flora H P van Leeuwen,Wouter Foppen,Merel A Timmer,Roger E G Schutgens,Simon C Mastbergen,Floris P J G Lafeber,Pim A de Jong,Kathelijn Fischer,Lize F D van Vulpen

Haemophilia : the official journal of the World Federation of Hemophilia（2023）

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摘要

Subclinical synovial proliferation, both active and inactive, was prevalent in patients with severe haemophilia A with access to prophylaxis and would be overlooked without routinely performed ultrasounds. Biochemical markers were unable to identify patients with active subclinical synovial proliferation.

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biomarkers, haemophilia, synovitis, ultrasonography

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