The Shank3-InsG3680( +/+) mouse model of autism spectrum disorder displays auditory avoidance in a novel behavioral test.

Ana Margarida Gonçalves,Nuno Sousa,Luis Jacinto,Patricia Monteiro

Frontiers in behavioral neuroscience（2023）

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摘要

These data suggest that - mutant mice might express an auditory hypersensitivity phenotype, further adding to the face validity of this genotype as an animal model of ASD.

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关键词

autism spectrum disorder (ASD), Shank3, auditory hypersensitivity, behavior, sensory alterations, animal model

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