Integrating serum metabolomics and network analysis to explore the antidepressant activity of crocin in rats with chronic unexpected mild stress-induced depression.

Pharmaceutical biology(2023)

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摘要
This study provides insights into the antidepressant therapeutic effect of crocin and its underlying mechanisms. The findings contribute to a better understanding of the metabolic mechanism involved in the anti-depressant effect of crocin, establishing a strong foundation for future research in this area.
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关键词
Traditional Chinese medicine,untargeted metabolomics,network pharmacology,interaction network,metabolism
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