Lipidomics of triglyceride-rich lipoproteins determines particle/THP-1 macrophages interaction and systemic inflammatory profile assessed by 1H-NMR

J. Moreno Vedia, R. Rosales, Y. Esteban, R. Rodríguez-Calvo,N. Plana, D. Ibarretxe, J. Girona, L. Masana

Atherosclerosis（2023）

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摘要

Background and Aims: High plasma triglyceride (TG) levels and chronic inflammation are important factors related to metabolic diseases, including diabetes. We aimed to study the lipidomic profile of triglyceride-rich lipoproteins (TRL) derived from patients with metabolic syndrome and the inflammatory effects mediated in vivo and in vitro.

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systemic inflammatory profile,macrophages,lipidomics,triglyceride-rich,h-nmr

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