The prevention against the deleterious effects of electronegative LDL on cardiomyocytes by HDL is partly impaired in type 2 diabetic patients

S. Benitez, J. Rives, N. Puig,I. Miñambres, P. Gil-Millán, M. Grau-Agramunt,A. Pérez,J.L. Sanchez-Quesada

Atherosclerosis(2023)

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摘要
Background and Aims: Type 2 diabetic (T2DM) patients have high incidence of heart failure and cardiovascular disease, which is associated with alterations in the lipid profile. Besides low levels of HDLc, these patients show dysfunctional HDL. We aimed to study the functionality of HDL from T2DM patients against the deleterious effect of electronegative LDL (LDL(-)) on cardiomyocytes.
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关键词
electronegative ldl,cardiomyocytes,hdl
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