Integrating bioinformatic analysis and detailed experiments reveal an EMT-related biomarker for clear cell renal cell carcinoma.

Yue Ge,Sheng Ma,Junbiao Zhang,Zezhong Xiong,Beining Li,Siquan Ma,Bo Liu,Xiangyang Yao,Zhihua Wang

Cancer medicine（2023）

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摘要

We identified the prognostic signature of seven genes based on EMT-related genes as prognostic biomarkers for ccRCC. Besides, OLFML2B was validated as a potential diagnostic and therapeutic target for ccRCC by our detailed experiments.

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关键词

biomarker, clear cell renal cell carcinoma, epithelial-mesenchymal transition, OLFML2B

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