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Abstract CT269: A Highly Sensitive and Specific PARylation Assay Confirms Significant and Durable Target Engagement by AZD5305 in Patients

Benedetta Lombardi,Paola Marco-Casanova, Athanasios Karapetsas, Mya Hornett,Edit Lukacs,Ko Sugibayashi,Sabina Cosulich, Adam Dowson,Ganesh Moorthy,Jessica Brown,Timothy A. Yap,Alison M. Schram,Judith Balmana,Stephen J. Luen,Seock-Ah Im,Adam Sharp,Richard Baird,Elizabeth A. Harrington,Spiros Linardopoulos

Cancer Research（2023）

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PARP Inhibitors

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