Multicomponent Reactions for Expeditious Construction of -Indole Carboxamide Amino Amides

A multicomponentreaction of N-indole carboxylicacids, aldehydes, amines, and C2 building blocks can be transformedto structurally diverse & beta;-indole carboxamide amino amides. Inthis multicomponent reaction, the ynamides and triazenyl alkynes actas the C2 building block, and this protocol features readily availablestarting materials, high atom economy, and mild reaction conditions.Besides, the acyl triazene group in the product can be easily transformedto differential groups to expand the structural diversity.