Preventive and Therapeutic Effects of La(III) Coordination Polymer on Thrombosis After Coronary Stent Implantation

In this paper, a novel three-dimensional (3D) coordination polymer (CP) based on La(III), namely, {[La(L)(H2O)3]Cl & BULL;H2O}n (1) (H2L is (4-(pyridyl-N-oxide)methylphosphonic acid), was self-assembled in success through diffusion approach at RT, which was characterized via SCXRD, EA and FT-IR. Photoluminescence studies show that complex 1 has a ligand-based blue emission. Its treatment activity on the thrombosis after coronary stent implantation was examined, simultaneously, the detailed mechanism was investigated. The weigh and length of the thrombus after coronary stent implantation in animals were tested and explored. Subsequently, the ELISA was em-ployed for the detection of coagulation factor levels existing in serum after the CP's treatment.