Application of the D 3 -creatine muscle mass assessment tool to a geriatric weight loss trial: A pilot study.

Among 24 older adults, significant WL with or without weighted vest use or resistance training over a 6-month period was associated with significant declines in all bioimaging metrics, while D Cr muscle mass and muscle function and strength were preserved. Treatment assignment for the trial remains blinded; therefore, full interpretation of these findings is limited. Future work in this area will assess change in D Cr muscle mass by parent trial treatment group assignment in all study participants.