Aggrandized Catalytic and Bactericidal Activity of Silver and Polyvinylpyrrolidone Capped Bismuth Oxybromide Quantum dots: In silico Molecular Docking Studies

The current study reports a novel synthesis of bismuth oxybromide (BiOBr) quantum dots (QDs) doped with different concentrations (3 and 6 wt%) of silver (Ag) and a fixed amount of polyvinylpyrrolidone (PVP). This research investigated the catalytic and antibacterial activity with evidential molecular docking analysis of Ag/PVP doped BiOBr QDs. The Ag and capping agent (PVP) were added to BiOBr as they regulate the growth of QDs and prevent their agglomeration that caused to increase in the catalytic and antibacterial activity. These binary dopants-based BiOBr QDs can be an ideal catalyst for disintegrating methylene blue dye and a potential inhibitor against the multiple drug resistance (MDR) Escherichia coli ( E. coli ) pathogen. Notably, 6% Ag/PVP doped BiOBr showed a significant catalytic reduction of methylene blue (MB) in a basic medium (pH ~ 12) compared to other environments. The results of the molecular docking investigation suggested that Ag/PVP-doped BiOBr QDs might be inhibitors of FabH and deoxyribonucleic acid (DNA) gyrase from E. coli , which was consistent with their In vitro antimicrobial activity.