Pertussis in Mexico from 2000 to 2019: A real-world study of incidence, vaccination coverage, and vaccine effectiveness

•In 2007, Mexico switched pertussis vaccines from whole-cell (wP) to acellular (aP).•There was increased pertussis notifications over the period 2000–2019 in Mexico.•Effectiveness was comparable (>95%) for 3 and 4 doses of wP and aP vaccines.•Vaccine coverage was >90% for dose 1, but decreased for each subsequent dose.•There is high protection against pertussis in children up to 4 years in Mexico.