Lack of concentration-dependent local toxicity of highly concentrated (5

Jasper G. Steverink,Floris R. van Tol,Suzanne Bruins,Andre J. Smorenburg,Marianna A. Tryfonidou,Bas J. Oosterman,Marijke R. van Dijk,Jos Malda,Jorrit-Jan Verlaan

Journal of Experimental Orthopaedics（2023）

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摘要

Various sustained-release formulations incorporate high bupivacaine concentrations but data on local toxicity is lacking. This study explores local toxic effects of highly concentrated (5

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关键词

Histopathology, Continuous wound infusion, Spinal surgery, Femoral surgery, Local anesthetics, Bupivacaine

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