Progesterone modulates extracellular heat-shock proteins and interlukin-1β in human choriodecidual after Escherichia coli infection.

Placenta(2023)

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摘要
we found that progesterone modulates the anti-inflammatory (eHsp-27) and pro-inflammatory (eHsp-60 and eHsp-70) levels of eHsp induced by E. coli infection in human choriodecidual tissue. eHsp-60 and eHsp-70 levels were not completely reversed; maintaining the secretion of IL-1β, which has been associated with adverse events during pregnancy.
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关键词
Chorioamnionitis, Extracellular heat shock proteins, Escherichia coli, Interleukin-1 beta, Human choriodecidual, Progesterone
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