Perillaldehyde Mitigates Ionizing Radiation-Induced Intestinal Injury by Inhibiting Ferroptosis via the Nrf2 Signaling Pathway.

Lin-Feng Tang,Xiaoming Ma,Li-Wei Xie,Hao Zhou,Jiahua Yu,Zhen-Xin Wang,Ming Li

Molecular nutrition & food research（2023）

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摘要

PAH inhibits ionizing radiation (IR)-induced ferroptosis and attenuates intestinal injury after irradiation by activating Nrf2 signaling. Therefore, PAH is a promising therapeutic strategy for IR-induced intestinal injury.

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关键词

ferroptosis, nuclear factor erythroid-2 related factor 2, perillaldehyde, radiation-induced intestinal injury, reactive oxygen species

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