Role of MLH1 and MSH2 deficiency in the development of tumorigenesis and chemo-tolerance of cervical Carcinoma: Clinical implications

Priyanka Dutta,Debolina Pal,Anup Roy,Ranajit Kumar Mandal,Chinmay Kumar Panda

Gene（2023）

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摘要

Schematic representation of gradual changes in the molecular profile of key regulatory Mismatch Repair genes (MLH1 and MSH2) from different layers of normal epithelium towards invasive cervical carcinoma and their association with the chemo-tolerance mechanism of the disease.

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关键词

Cervical Carcinoma,MLH1,MSH2,Cisplatin,MMR deficiency,Disease-recurrence

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