Toxic megacolon due to acute severe ulcerative colitis in the era of biologic treatment.

ANZ Journal of SurgeryEarly View IMAGES FOR SURGEONS Toxic megacolon due to acute severe ulcerative colitis in the era of biologic treatment Elise Ho MD, Elise Ho MD orcid.org/0000-0002-3179-1912 Colorectal Surgery Department, St Vincent's Public Hospital Melbourne, Melbourne, Victoria, Australia Contribution: Writing - original draft, Writing - review & editingSearch for more papers by this authorJawed Noori MBBS, FRACS, Jawed Noori MBBS, FRACS Colorectal Surgery Department, St Vincent's Public Hospital Melbourne, Melbourne, Victoria, Australia Contribution: SupervisionSearch for more papers by this authorRodney Woods MBBS, FRACS, Rodney Woods MBBS, FRACS Colorectal Surgery Department, St Vincent's Public Hospital Melbourne, Melbourne, Victoria, Australia Contribution: Conceptualization, SupervisionSearch for more papers by this authorJames Keck MBBS, FRACS, James Keck MBBS, FRACS Colorectal Surgery Department, St Vincent's Public Hospital Melbourne, Melbourne, Victoria, Australia Contribution: Conceptualization, SupervisionSearch for more papers by this authorCorina Behrenbruch MBBS Hons, FRACS, Corina Behrenbruch MBBS Hons, FRACS orcid.org/0000-0002-2942-2480 Colorectal Surgery Department, St Vincent's Public Hospital Melbourne, Melbourne, Victoria, Australia Contribution: Conceptualization, Supervision, Writing - review & editingSearch for more papers by this author Elise Ho MD, Elise Ho MD orcid.org/0000-0002-3179-1912 Colorectal Surgery Department, St Vincent's Public Hospital Melbourne, Melbourne, Victoria, Australia Contribution: Writing - original draft, Writing - review & editingSearch for more papers by this authorJawed Noori MBBS, FRACS, Jawed Noori MBBS, FRACS Colorectal Surgery Department, St Vincent's Public Hospital Melbourne, Melbourne, Victoria, Australia Contribution: SupervisionSearch for more papers by this authorRodney Woods MBBS, FRACS, Rodney Woods MBBS, FRACS Colorectal Surgery Department, St Vincent's Public Hospital Melbourne, Melbourne, Victoria, Australia Contribution: Conceptualization, SupervisionSearch for more papers by this authorJames Keck MBBS, FRACS, James Keck MBBS, FRACS Colorectal Surgery Department, St Vincent's Public Hospital Melbourne, Melbourne, Victoria, Australia Contribution: Conceptualization, SupervisionSearch for more papers by this authorCorina Behrenbruch MBBS Hons, FRACS, Corina Behrenbruch MBBS Hons, FRACS orcid.org/0000-0002-2942-2480 Colorectal Surgery Department, St Vincent's Public Hospital Melbourne, Melbourne, Victoria, Australia Contribution: Conceptualization, Supervision, Writing - review & editingSearch for more papers by this author First published: 31 August 2023 https://doi.org/10.1111/ans.18683Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat No abstract is available for this article. References 1Kedia S, Ahuja V, Tandon R. Management of acute severe ulcerative colitis. World J. Gastrointest. Pathophysiol. 2014; 15: 579–588. 2Clark N, MacIsaac M, Little R et al. Have changing practices in salvage medical options affected colectomy rates in acute severe ulcerative colitis? Intern. Med. J. 2023. Epub ahead of print. https://doi.org/10.1111/imj.16074 3Dayan B, Turner D. Role of surgery in severe ulcerative colitis in the era of medical rescue therapy. World J. Gastroenterol. 2012; 7: 3833–3838. 4Desai J, Elnaggar M, Hanfy A, Doshi R. Toxic megacolon: background, pathophysiology, management challenges and solutions. Clin. Exp. Gastroenterol. 2020; 13: 203–210. 5Coakley BA, Telem D, Nguyen S, Dallas K, Divino CM. Prolonged preoperative hospitalization correlates with worse outcomes after colectomy for acute fulminant ulcerative colitis. Surgery 2013; 153: 242–248. 6Leeds IL, Sundel MH, Gabre-Kidan A et al. Outcomes for ulcerative colitis with delayed emergency colectomy are worse when controlling for preoperative risk factors. Dis. Colon Rectum 2019; 62: 600–607. 7Leeds IL, Truta B, Parian AM et al. Early surgical intervention for acute ulcerative colitis is associated with improved postoperative outcomes. J. Gastrointest. Surg. 2017; 21: 1675–1682. 8Saha SK, Panwar R, Kumar A et al. Early colectomy in steroid-refractory acute severe ulcerative colitis improves operative outcome. Int. J. Colorectal Dis. 2018; 33: 79–82. 9Spinelli A, Bonovas S, Burisch J et al. ECCO guidelines on therapeutics in ulcerative colitis: surgical treatment. J. Crohns Colitis 2022; 23: 179–189. 10Andersson P, Söderholm JD. Surgery in ulcerative colitis: indication and timing. Dig. Dis. 2009; 27: 335–340. Early ViewOnline Version of Record before inclusion in an issue ReferencesRelatedInformation