Viral Determinants of Acute COVID-19 Symptoms in a Nonhospitalized Adult Population in the Pre-Omicron Era.

Sarah A Goldberg,Scott Lu,Miguel Garcia-Knight,Michelle C Davidson,Michel Tassetto,Khamal Anglin,Jesus Pineda-Ramirez,Jessica Y Chen,Paulina R Rugart,Sujata Mathur,Carrie A Forman,Kevin C Donohue,Glen R Abedi, Sharon Saydah,Melissa Briggs-Hagen,Claire M Midgley,Raul Andino,Michael J Peluso, David V Glidden,Jeffrey N Martin,J Daniel Kelly

Open forum infectious diseases（2023）

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摘要

We found evidence to support the association of viral RNA load and infectious virus on some, but not all symptoms. Fever was most strongly associated with the presence of infectious virus; this may support the potential for symptom-based isolation guidance for COVID-19.

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viral determinants,symptoms,acute,non-hospitalized,pre-omicron

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