Clinical features of COVID-19 in Italian outpatient children and adolescents during Parental, Delta, and Omicron waves: a prospective, observational, cohort study.

Costanza Di Chiara,Riccardo Boracchini,Giulia Sturniolo,Alessia Barbieri,Paola Costenaro,Sandra Cozzani,Marica De Pieri,Cecilia Liberati, Annachiara Zin,Andrea Padoan,Francesco Bonfante,Fatima Kakkar,Anna Cantarutti,Daniele Donà,Carlo Giaquinto

Frontiers in pediatrics（2023）

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摘要

This study showed differences in COVID-19 clinical presentation among infants, children, and adolescents and confirmed Omicron infection is more likely to be associated with upper respiratory symptoms. However, further population-based studies are needed to support these findings. In addition, active surveillance will play a crucial role in assessing the disease severity of future VOCs.

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COVID-19, SARS-CoV-2, clinical manifestations, symptoms, pediatric population, children, variants of concern

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