Validation of the Cognitive Assessment Instrument for Obsessions and Compulsions (CAIOC-13) in an Indian Sample

Background Brief self-report measures of cognition are advantageous for flagging significant cognitive dysfunction and minimising the need for extensive neuropsychological assessments. The Cognitive Assessment Instrument for Obsessions and Compulsions (CAIOC-13) is a recently developed 13-item self-rated scale, assessing everyday functional difficulties resulting from cognitive dysfunction specific to those reported by individuals with Obsessive-Compulsive Disorder (OCD) e.g., difficulties with reading, making choices, slowness, perfectionism & procrastination). This study was undertaken to validate the CAIOC-13 in an Indian sample of individuals with OCD. Material and Methods A total of 75 subjects with OCD and 81 non-clinical controls completed the CAIOC-13, the Perceived Deficits Questionnaire (PDQ) and the Dysfunctional Attitude Scale-Short Form (DAS-SF1). Pearson’s r correlation was used to establish the convergent and divergent validity with PDQ and DAS-SF1 respectively; the Receiver Operating Characteristic (ROC) curve was used to analyze the discriminant validity, and the factorial structure was evaluated using the Principal Component Analysis (PCA). Results CAIOC-13 scale scores showed a strong significant correlation (r = 0.56 p <0.001) with PDQ scores and a weak correlation with DAS-SF1 scores (r = 0.33 p = 0.003). Area Under the ROC curve (AUC) value was found to be 0.92 indicating that the CAIOC-13 could accurately discriminate between OCD and controls. The PCA analysis also showed a strong loading on a single component. Conclusion The results suggest that the CAIOC-13 is a valid tool for briefly assessing cognitive deficits in individuals with OCD in India. Future studies may also examine the correlation of CAIOC-13 with standardized neuropsychological assessments. ### Competing Interest Statement The authors have declared no competing interest. ### Funding Statement This study did not receive any funding ### Author Declarations I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained. Yes The details of the IRB/oversight body that provided approval or exemption for the research described are given below: Institute Ethics Committee of National Institute of Mental Health and Neurosciences (NIMHANS), Bangalore gave ethical approval for this work on 1st february 2021. I confirm that all necessary patient/participant consent has been obtained and the appropriate institutional forms have been archived, and that any patient/participant/sample identifiers included were not known to anyone (e.g., hospital staff, patients or participants themselves) outside the research group so cannot be used to identify individuals. Yes I understand that all clinical trials and any other prospective interventional studies must be registered with an ICMJE-approved registry, such as ClinicalTrials.gov. I confirm that any such study reported in the manuscript has been registered and the trial registration ID is provided (note: if posting a prospective study registered retrospectively, please provide a statement in the trial ID field explaining why the study was not registered in advance). Yes I have followed all appropriate research reporting guidelines, such as any relevant EQUATOR Network research reporting checklist(s) and other pertinent material, if applicable. Yes All data produced in the present study are available upon reasonable request to the authors