PIEZO1 promotes ATP release from periodontal ligament cells following compression force.

Seiwa Horie,Chihiro Nakatomi,Misa Ito-Sago,Aoi Morii,Ai Orimoto,Hiroshi Ikeda,Chia-Chien Hsu,Mako Naniwa,Masahiro Mizuhara, Kaori Gunjigake,Tatsuo Kawamoto,Kentaro Ono

European journal of orthodontics（2023）

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摘要

PIEZO1 on the cell membranes of HPdLFs is activated by compression force and then induces ATP release via intracellular Ca2+-dependent exocytosis and ATP-permeable channels.

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关键词

PIEZO1,TRPA1,adenosine triphosphate,bone remodelling,orthodontics,pain

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