Expression analysis, clinical significance and potential function of PLXNB2 in acute myeloid leukaemia.

Zhibo Guo,Dan Guo,Desheng Kong,Sicheng Bian,Linlin Zhao,Qi Li,Leilei Lin, Jiali Hao,Lili Sun,Yinghua Li

Molecular biology reports（2023）

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摘要

The overexpression of PLXNB2 is an adverse prognostic factor in adult AML patients and could be used as a potential biomarker. PLXNB2 might exert an oncogenic role by modulating immune functions, endothelial cell functions and cell interactions. AML patients with high PLXNB2 expression could benefit more from HSCT.

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Acute myeloid leukaemia,Bioinformatics,PLXNB2,Prognosis,TCGA database

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