Renal Disorders with Oral Tyrosine Kinase Inhibitors in Metastatic Colorectal Cancer: An Analysis from the FDA Adverse Event Reporting System Database.

Giulia Russo,Maria Antonietta Barbieri,Emanuela Elisa Sorbara,Giuseppe Cicala,Tindara Franchina,Mariacarmela Santarpia,Nicola Silvestris,Edoardo Spina

Biomedicines（2023）

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摘要

these findings highlight some not extensively reported renal ADRs that require further investigations to better characterize the safety profiles of REG and ENC in patients with mCRC.

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关键词

adverse drug reactions,colorectal cancer,encorafenib,pharmacovigilance,regorafenib,renal disorders,tyrosine kinase inhibitors

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