CircSOD2 polarizes macrophages towards the M1 phenotype to alleviate cisplatin resistance in gastric cancer cells by targeting the miR-1296/STAT1 axis

Bing Qu,Jiasheng Liu,Zhiyang Peng,Zhe Xiao,Shijun Li,Jianguo Wu,Shengbo Li,Jianfei Luo

Gene（2023）

引用 1|浏览6

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摘要

•CircSOD2 was upregulated in M1 macrophages.•CircSOD2 enhanced M1 polarization.•Macrophages overexpressing circSOD2 enhanced the cisplatin effect.•CircSOD2 mediated STAT1 expression by interacting with miR-1296.

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关键词

circSOD2,Macrophage polarization,Cisplatin resistance,Gastric cancer

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