Phenotypic characteristics of circulating tumor cells and predictive impact for efficacy of chemotherapy in patients with pancreatic cancer: a prospective study.

Hee Seung Lee, Eun Hye Jung,Hyejung Shin, Chan Su Park,Soo Been Park,Dawoon E Jung, Galam Leem, So Jung Kim,Jung Hyun Jo,Moon Jae Chung,Jeong Youp Park,Seungmin Bang,Seung Woo Park,Si Young Song

Gastroenterology（2023）

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摘要

Our study's findings suggest that CTCs can serve as predictive biomarkers of clinical outcomes in patients with PDAC receiving palliative chemotherapy. In particular, the total CTC count and vimentin-positive CTCs showed changes associated with the chemotherapy response.

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circulating tumor cells,pancreatic cancer,ep83,chemotherapy

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