Spectral flow cytometry identifies distinct nonneoplastic plasma extracellular vesicle phenotype in glioblastoma patients.

Abudumijiti Zack Aibaidula,Cori E Fain,Luz Cumba Garcia, Annelise Wier,Samantha M Bouchal,Megan M Bauman,Mi-Yeon Jung,Jann N Sarkaria,Aaron J Johnson,Ian F Parney

Neuro-oncology advances（2023）

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摘要

Multiparametric analysis demonstrates that GBM patients have a distinct nonneoplastic plasma EV phenotype compared to ND. This simple rapid analysis can be performed without purifying tumor EVs and may serve as the basis of a liquid biopsy.

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glioblastoma,non-neoplastic

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