A review collection on immunometabolism

Recent studies indicate an intimate link between immunity and metabolism,spawning the now burgeoning field of immunome-tabolism.What is the rationale for such a link?On the one hand,immune responses are energetically very demanding.Clonal expansion of T and B cells,increased production of inflammatory cytokines and antibodies by activated macrophages and plasma cells,and recruitment of immune cells to the site of infec-tion are all thought to impose a high metabolic and energetic demand.