PD-L1 expression is associated with senescence in HNSCC cells after irradiation

Annette Affolter,Claudia Scherl,Anne Lammert,Alexya Azhakesan,Johann Kern,Jens Fleckenstein,Nicole Rotter, Luis Bugia

Laryngo-rhino-otologie（2023）

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摘要

Introduction Fractionated irradiation (FR) can cause premature senescence of tumor cells. Interactions between senescence and the immune system are poorly understood to date. Therefore, our study addresses the detection of senescence-associated modulation of PD-L1 expression under FR in the HNSCC model.

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关键词

hnscc cells,senescence

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