Dysglycemia in non-functioning pancreatic neuroendocrine tumors (NF-PNET): Further insights into an under recognized entity

•Pancreatic neuroendocrine tumors (PNETs) are rare, but their incidence has risen significantly in recent years.•Diabetes mellitus (DM) is clearly recognized in association with chronic pancreatitis and pancreatic cancer, but it has not been well-characterized in relation to non-functioning (NF)- PNETs.•We found a high rate of impaired glucose metabolism, either DM or Pre-DM, in a large cohort of subjects with NF-PNETs.•The high prevalence of diabetes/pre-diabetes was not related to obesity or tumor size.•The study highlights and reinforces the increased rate and association of DM and pre-DM with NF-PNETS. In addition, it adds a novel piece of information by evaluating the effect of tumor size, grade and tumor location on this association.